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. 2023 Jan 24;18(1):e0279752. doi: 10.1371/journal.pone.0279752

Fig 1. Effects of SQFZ or SQFZ + cisplatin on tumour growth in MDA-MB-231/DDP+M2 xenografts.

Fig 1

BALB/c nude mice bearing MDA-MB-231/DDP+M2 in fat pads as xenografts were treated daily with i.p. injections of control or SQFZ 20, 40, 60 mL/kg, Cisplatin 2 mg/kg, SQFZ 40 mL/kg + Cisplatin, Verapamil 1.35 mg/kg, or Verapamil + Cisplatin for 4 weeks. Tumour volumes (A) and mouse body weights (B) were measured as described. Data are presented as the means ± SD (n = 10). *P < 0.05 compared with Cisplatin alone.