Table 3.

Z-score values for each cortical region per patient. Data were acquired by analyzing semi-quantitative data on ¹⁸F-FDG PET/CT imaging

Brain area	1 (58. F)	2 (50. M)	3 (65. M)	4 (55. M)	5 (56. F)	6 (54. F)	7 (55. M)	Mean	SD
Right lateral prefrontal	0.51	1.01	0.28	− 0.89	1.23	− 2.22	− 0.73	− 0.12	1.23
Left lateral prefrontal	0.43	1.19	0.27	− 0.61	0.65	− 2.30	− 0.73	− 0.16	1.16
Right prefrontal medial	0.09	0.32	− 1.09	− 0.93	− 0.23	− 2.27	− 0.96	− 0.72	0.88
Left prefrontal medial	0.02	0.25	− 0.85	− 0.78	0.08	− 2.12	− 0.76	− 0.59	0.82
Right sensorimotor	0.37	1.05	0.95	− 0.64	0.82	− 1.73	0.22	0.15	1.01
Left sensorimotor	0.06	0.80	0.16	− 0.35	0.62	− 1.98	0.70	0.00	0.96
Right anterior cingulate	1.08	0.63	− 0.83	− 0.02	0.61	− 0.64	0.48	0.19	0.71
Left anterior cingulate	0.83	0.69	− 0.43	0.21	0.54	− 0.63	0.21	0.20	0.55
Right posterior cingulate	0.42	0.20	− 0.48	− 0.99	0.20	− 2.00	− 0.10	− 0.39	0.86
Left posterior cingulate	0.58	0.66	− 0.09	− 0.68	0.36	− 1.95	− 0.32	− 0.21	0.91
Right precuneus	0.51	0.19	0.22	− 1.04	0.43	− 2.23	− 0.32	− 0.32	1.00
Left precuneus	0.55	0.99	0.00	− 0.69	0.38	− 2.18	− 0.07	− 0.15	1.04
Right superior parietal	1.06	− 0.04	0.52	− 0.49	0.58	− 1.46	0.76	0.13	0.87
Left superior parietal	0.94	− 0.13	− 0.78	− 0.50	− 0.02	− 2.25	1.49	− 0.18	1.21
Right inferior parietal	1.17	0.40	− 0.21	− 1.11	1.04	− 1.69	− 0.23	− 0.09	1.06
Left inferior parietal	0.55	0.61	− 0.67	− 0.64	0.98	− 2.13	− 0.21	− 0.22	1.06
Right lateral occipital	1.42	1.32	0.66	− 0.04	1.32	− 1.67	0.61	0.52	1.10
Left lateral occipital	1.27	1.23	0.60	0.18	1.37	− 1.75	0.97	0.55	1.10
Right primary visual	2.60	1.70	1.39	0.00	0.75	− 1.74	2.73	1.06	1.57
Left primary visual	2.04	1.44	1.00	− 0.23	1.27	− 1.81	2.44	0.88	1.46
Right lateral temporal	0.35	0.65	− 0.45	− 0.97	0.99	− 1.61	− 0.67	− 0.24	0.94
Left lateral temporal	− 0.10	0.49	− 1.11	− 0.72	0.75	− 1.61	− 0.62	− 0.42	0.85
Right temporal mesial	0.02	0.89	− 1.69	− 0.81	0.02	− 0.58	− 1.33	− 0.50	0.88
Left temporal mesial	− 0.41	0.73	− 2.85	− 0.72	0.09	− 0.93	− 1.07	− 0.74	1.12
Pons	− 2.13	2.68	− 1.83	− 0.54	0.71	0.25	0.16	− 0.10	1.63

Patients’ quantified uptake was compared with reference values obtained from healthy age-matched controls. Deviation from normal values was deemed either statistically significant or non-significant using a -2 SD cut-off