Table 2.

Pharmacy Services Conducted ≥50% of the Time

Pharmacy service	Phase 1 cancer trial services performed by pharmacists	≤40 Phase 1 cancer clinical trials, % (N = 16)	>40 Phase 1 cancer clinical trials, % (N = 17)
Pretrial implementation support	Serve as a principal investigator	0	0
	Serve as a coinvestigator	6.2	5.9
	Participate in development of investigator-initiated trials	12.5	17.6
	Serve as a member of Institutional Review Board	87.5	82.4
Phase 1 clinical trial implementation support	Dedicate a pharmacist to work with phase 1 cancer trials	50	58.9
	Educate research staff on investigational drugs	62.5	70.6
	Prepare patient counseling material	31.2	29.4
	Serve as key personnel in the consenting process	6.2	5.9
	Individuals are an Investigational Drug Service pharmacist	81.2	70.6
	Individuals are an oncology clinical specialist	56.2	64.7
	Pharmacists are involved with direct subject care	18.8	47
	Pharmacists have an academic role with a pharmacy/medicine school	31.2	47
Medication profile review	Document medication list for phase 1 trial subjects before trial initiation	18.8	41.1
	Perform medication reconciliation	37.5	41.1
	Screen subject profile for potential drug–drug interactions	62.5	76.4
	Clinically review prescribed investigational drug orders before dispensing	87.5	82.4
Medication therapy management	Counsel trial subjects	50	47
	Recommend dose adjustments per protocol	62.5	64.7
	Perform therapeutic drug monitoring	25	35.3
	Determine protocol compliance with prohibitive medications	56.2	64.7
Miscellaneous support	Serve on the data safety monitoring committee	31.2	47
	Complete safety adverse event reports	6.2	5.9
	Contribute to presentation or publication of phase 1 trial findings	0	11.8