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GLEXG treatment activated the Keap1/Nrf2 signaling pathway. (A) Representative gel images of Keap1 and HO1 and relative protein levels in each group. (B) Representative gel images of nuclear Nrf2 and cytoplasmic Nrf2, and relative protein levels in each group. (C) Relative mRNA expression levels of Keap1, HO1 and Nrf2 in each group. Data are shown as the means ± SEM. *p < 0.05; **p < 0.01; ***p < 0.001; ****p < 0.0001 vs. the model group, respectively.
