Table 4.
Risk factors for mortality in patients with SCLC assessed by Cox proportional hazards model
| Univariate analysis | Multivariate analysis | |||||
|---|---|---|---|---|---|---|
|
|
|
|||||
| Hazard ratio | 95% CI | p-value | Hazard ratio | 95% CI | p-value | |
| Age | 1.042 | 1.028–1.056 | < 0.001 | 1.041 | 1.026–1.057 | < 0.001 |
|
| ||||||
| Male sex | 1.079 | 0.796–1.463 | 0.622 | |||
|
| ||||||
| Ever-smoker | 0.685 | 0.504–0.929 | 0.015 | 0.736 | 0.509–1.062 | 0.101 |
|
| ||||||
| BMI | 1.000 | 0.997–1.004 | 0.787 | |||
|
| ||||||
| Performance status | ||||||
|
| ||||||
| 0–1 (ref) | 1.000 | 1.000 | ||||
|
| ||||||
| 2–4 | 1.943 | 1.391–2.714 | < 0.001 | 1.838 | 1.305–2.587 | < 0.001 |
|
| ||||||
| Clinical stage | ||||||
|
| ||||||
| LD (ref) | 1.000 | 1.000 | ||||
|
| ||||||
| ED | 1.961 | 1.542–2.493 | < 0.001 | 2.144 | 1.636–2.810 | < 0.001 |
|
| ||||||
| Treatment | ||||||
|
| ||||||
| Anti-cancer treatment (ref) | 1.000 | |||||
|
| ||||||
| Best supportive care | 1.160 | 0.924–1.455 | 0.200 | |||
BMI, body mass index; CI, confidence interval; ED, extensive disease; LD, limited disease; SCLC, small cell lung cancer.