Table 3.
Safety of the COVID-19 vaccines | Odds ratio | 95% confidence interval | P-value | Study ID |
---|---|---|---|---|
Obstetric and neonatal outcomes (vaccinated pregnant women vs unvaccinated pregnant women) | Theiler et al.[16];Wainstock et al.[17]; Goldshtein et al.[12]; Rottenstreich et al.[18]; Bookstein Peretz et al.[21]; Blakeway et al.[19]; Lipkind et al.[20]; Shimabukuro et al.[26]; Kachikis et al.[22]; Trostle et al.[23]; Zauche et al.[24]; Kharbanda et al.[25]; Magnus et al.[15] |
|||
Premature delivery | 0.83 | 0.65-1.06 | 0.13 | |
Placental abruption | 0.60 | 0.29-1.21 | 0.15 | |
Postpartum hemorrhage | 0.91 | 0.64-1.29 | 0.59 | |
Miscarriage | 1.12 | 1.00-1.27 | 0.05 | |
Stillbirth | 1.42 | 0.53-3.76 | 0.49 | |
Small for gestational age infant | 1.03 | 0.90-1.18 | 0.70 | |
Local and systemic reactogenicity (pregnant women vs nonpregnant women) | ||||
Muscle pain (first dose) | 0.45 | 0.22-0.93 | 0.03 | |
Muscle pain (second dose) | 1.28 | 0.73-2.23 | 0.39 | |
Fatigue (first dose) | 0.90 | 0.63-1.28 | 0.56 | |
Fatigue (second dose) | 0.89 | 0.65-1.22 | 0.48 | |
Fever (first dose) | 1.02 | 0.12-8.61 | 0.98 | |
Fever (second dose) | 0.65 | 0.42-1.01 | 0.05 |