Table 2.
Distribution of C677T MTHFR polymorphism in the breast cancer group according to genetic models.
| Genotype/allele | Cases | Controls | OR (95% CI) | p |
|---|---|---|---|---|
| N = 127 | N = 160 | |||
| CC | 112 (88.2) | 145 (90.6) | Reference | |
| CT | 14 (11.0) | 14 (8.8) | 1.29 (0.59–2.82) | 0.52 |
| TT | 1 (0.8) | 1 (0.6) | 1.29 (0.08–20.92) | 0.85 |
| TT + CT | 15 (11.8) | 15 (10.0) | 1.29 (0.61–2.76) | 0.50 |
| CC + CT | 126 (99.2) | 159 (99.4) | Reference | |
| TT | 1 (0.8) | 1 (0.6) | 1.26 (0.08–20.37) | 0.87 |
| C | 238 (93.7) | 304 (95.0) | Reference | |
| T | 16 (6.3) | 16 (5.0) | 1.28 (0.62–2.61) | 0.50 |
N= number; CI: confidence interval; p: p value; TT + CT vs. CC: the dominant model; TT vs. CC + CT: the recessive model; T vs. C: the additive model;