Figure 1.

Axial contrast-enhanced T1-weighted (A, E), Ktrans (B, F), and plasma volume (C, G) images with overlaid segmentation in 2 patients (top and bottom rows). Both lesions presented with ill-defined cystic or necrotic heterogeneously enhancing lesions with peripherally increased Ktrans and plasma volume. Corresponding histopathologic sections (H&E, 10X) showed almost entirely devitalized, necrotic tissue (D) in a patient with pseudoprogression who survived for another 29.2 months, and viable-appearing glioblastoma (H) in a patient who had recurrent tumor and survived for only 3.2 months.