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. 2023 Jan 9;29(1):104–114. doi: 10.1038/s41591-022-02128-z

Extended Data Fig. 6. Longitudinal immunophenotyping of memory subtypes within circulating afami-cel.

Extended Data Fig. 6

Percentage of parent population (a) CD4+ Dextramer+ and (b) CD8+ Dextramer+ within the respective sub-population flow gate in MP (manufactured product) and peripheral blood mononuclear cell samples at post-infusion timepoints (D, day; W, week; M, month, EOT, end of treatment). CM (central memory CD45RA-CCR7+); EM (effector memory CD45RA-CCR7-); EMRA (effector memory RA+, CD45RA+ CCR7-); SCM (stem cell memory, CD45RA+ CCR7+). Data are grouped by best overall response resulting from the infusion. PR (partial response), n = 9 patients; SD (stable disease), n = 17 patients; PD (progressive disease), n = 6 patients.