Table 1.
Summary of patient characteristics (mITT population, N = 38)
| Parameter | Category | Statistic | Overall (N = 38) |
|---|---|---|---|
| Age (years) | N | 38 | |
| Mean (standard deviation) | 56.4 (12.59) | ||
| Median | 58.0 | ||
| Min, max | 31, 78 | ||
| Age categorization | <65 years | n (%) | 28 (73.7) |
| ≥65 years | n (%) | 10 (26.3) | |
| Sex | Male | n (%) | 22 (57.9) |
| Female | n (%) | 16 (42.1) | |
| Ethnicity | Hispanic/Latino | n (%) | 2 (5.3) |
| Not Hispanic/Latino | n (%) | 36 (94.7) | |
| Race | White | n (%) | 35 (92.1) |
| Asian | n (%) | 3 (7.9) | |
| Primary tumor type | Esophageal | n (%) | 2 (5.3) |
| Gastric | n (%) | 1 (2.6) | |
| Head and neck | n (%) | 3 (7.9) | |
| Melanoma | n (%) | 1 (2.6) | |
| NSCLC | n (%) | 2 (5.3) | |
| Ovarian | n (%) | 9 (23.7) | |
| Urothelial | n (%) | 2 (5.3) | |
| MRCLS | n (%) | 2 (5.3) | |
| SS | n (%) | 16 (42.1) | |
| ECOG score | 0 | n (%) | 13 (34.2) |
| 1 | n (%) | 25 (65.8) | |
| Time from initial diagnosis to T cell infusion (months)a | Mean (standard deviation) | 51.4 (40.33) | |
| Median | 40.4 | ||
| Min, max | 7.3, 205.5 | ||
| Prior lines of systemic therapy | Mean (standard deviation) | 3.2 (1.88) | |
| Median | 3.0 | ||
| Min, max | 1, 8 | ||
| Total transduced cells (×109) | Mean (standard deviation) | 6.1213 (3.422688) | |
| Median | 6.4022 | ||
| Min, max | 0.1, 9.9756 |
aTime from initial diagnosis to T cell infusion in months was calculated as: (T cell infusion date – date since initial diagnosis + 1) × (12/365.25).
max, maximum; min, minimum; N, total number of patients; n, number of patients.