Table 1.
Demographics and baseline characteristics of participants in the analysis set
| All participantsa (n = 128) | Surgery (n = 78) | Medical (n = 50) | P value for differences between treatment groups | |
|---|---|---|---|---|
| Sex | 0.703 | |||
| Male | 87 (68.0%) | 54 (69.2%) | 33 (66.0%) | |
| Female | 41 (32.0%) | 24 (30.8%) | 17 (34.0%) | |
| Median age (years) | 52 (42.5–60.0) | 52 (43–60) | 52.5 (41–61) | 0.874 |
| Median BMI (kg m−2) | 29.7 (26.7–34.0) | 30.5 (26.3–34.8) | 29.1 (26.9–33.2) | 0.336 |
| Ethnicity | 0.007 | |||
| White | 75 (58.6%) | 53 (67.9%) | 22 (44%) | |
| Blackb | 38 (29.7%) | 15 (19.2%) | 23 (46%) | |
| Asian | 14 (10.9%) | 9 (11.5%) | 5 (10%) | |
| Other | 1 (0.8%) | 1 (1.3%) | 0 (0%) | |
| Clinic BP at screening | ||||
| SBP median (mmHg) | 148 (138–166) | 149 (138–166) | 145 (138–166) | 0.705 |
| DBP median (mmHg) | 91 (82–103) | 91 (81–102) | 89 (84–104) | 0.667 |
| Median NDC | 2 (2–3) | 2 (2–3) | 2 (2–3) | 0.929 |
| Median DDD | 3.5 (2.1–6.0) | 4.0 (2.3–6.5) | 3.1 (2.0–6.0) | 0.199 |
aThe demographics and baseline characteristics of patients in the analysis set (that is, those who had completed their allocated treatment and follow-up (6 months post-adrenalectomy or after 9–12 months of medical therapy) at the time the study were censored). Data for patients managed with surgery or medical therapy are also shown.
bBlack patients comprised 40% of 108 patients recruited in London hospitals, where 14% of the local population is Black.
Numbers in brackets indicate percentages, whereas ranges in brackets indicate first and third quartiles. For categorical data, the Fisher’s exact test was used. For continuous data, the Mann–Whitney–Wilcoxon test was used.
BMI, body mass index; BP, blood pressure; DDD, defined daily dose of antihypertensive medication; DBP, diastolic blood pressure; NDC, number of different classes of antihypertensive medication.