Fig. 3. ORT formation in CHM.

The figure discloses baseline BAF, structural OCT and magnified structural OCT (A, B, C, respectively) and last follow-up images (D, E, F, respectively). Although some ORT are already present at baseline, during the follow-up it is possible to see the further development of a ORT at the border of the partially preserved retinal islet area. The mandatory condition for the ORT formation is the presence of a partially preserved ellipsoid zone at baseline (orange asterisk). In the absence of this condition, it is possible to observe only some minor atrophic changes (blue asterisk), making the progression of outer retinal atrophy somehow symmetric. The ORT formation is followed also by the progression of outer retinal atrophy, as evinced by the expansion of the window “bar code” effect detected by structural OCT (colour figure online).