. 2022 Jan 28;37(2):338–343. doi: 10.1038/s41433-022-01953-3

Table 1.

Quantitative OCT and OCTA analysis of 16 choroideremia eyes and 20 age-matched controls.

Quantitative OCT and OCTA analysis
	Baseline	Last F/U	Controls	p Value
CMT (µm)	242 ± 18	238 ± 21	241 ± 11	>0.05
CMT (µm)	>0.05		241 ± 11	>0.05
Mean ELM Thickness (µm)	11 ± 1	8 ± 1	13 ± 1	<0.01
Mean ELM Thickness (µm)	<0.01		13 ± 1	<0.01
ELM Thickness in the region of atrophy progression (µm)	8 ± 1	0 ± 0	N/A	N/A
ELM Thickness in the region of atrophy progression (µm)	<0.01		N/A	N/A
Mean ELM Reflectivity	0.68 ± 0.13	0.65 ± 0.14	0.68 ± 0.06	>0.05
Mean ELM Reflectivity	>0.05		0.68 ± 0.06	>0.05
ELM Reflectivity in the region of atrophy progression	0.49 ± 0.25	N/A	N/A	N/A
ELM Reflectivity in the region of atrophy progression	<0.01		N/A	N/A
Partially preserved islet area (mm²)	10 ± 7	7 ± 5	N/A	N/A
Partially preserved islet area (mm²)	>0.05		N/A	N/A
Partially preserved islet area + Surrounding Borders (mm²)	12 ± 5	9 ± 4	N/A	N/A
Partially preserved islet area + Surrounding Borders (mm²)	>0.05		N/A	N/A
VD SCP	0.4 ± 0.02	0.39 ± 0.03	0.4 ± 0.02	>0.05
VD SCP	>0.05		0.4 ± 0.02	>0.05
VD DCP	0.02 ± 0.01	0.02 ± 0.02	0.4 ± 0.03	<0.01
VD DCP	>0.05		0.4 ± 0.03	<0.01
VD CC Mean	0.5 ± 0.02	0.49 ± 0.03	0.5 ± 0.02	>0.05
VD CC Mean	>0.05		0.5 ± 0.02	>0.05
VD CC Partially Preserved Islet	0.5 ± 0.04	0.49 ± 0.03	0.5 ± 0.02	>0.05
VD CC Partially Preserved Islet	>0.05		0.5 ± 0.02	>0.05
VD CC Surrounding Borders	0.41 ± 0.05	0.39 ± 0.02	0.5 ± 0.02	<0.01
VD CC Surrounding Borders	>0.05		0.5 ± 0.02	<0.01
VD CC in the region of atrophy progression	0.42 ± 0.08	0.39 ± 0.05	0.5 ± 0.02	<0.01
VD CC in the region of atrophy progression	>0.05		0.5 ± 0.02	<0.01

CMT central macular thickness, ELM external limiting membrane, VD vessel density, SCP superficial capillary plexus, DCP deep capillary plexus, CC choriocapillaris.