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. 2023 Jan 24;14:396. doi: 10.1038/s41467-023-35907-4

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — a Effect of different concentrations (0.05, 0.1, 0.2, 0.5, 1.0, and 2.0 mg/mL from left to right in the graph) of d-SMG on cell viability by MTT method (n = 3 cells examined over 3 independent experiments in each group). b Effect of d-SMGs on hemolysis (n = 3 biologically independent samples in each group). c Effect of d-SMGs and their s-GAGs on APTT of human coagulation control plasma (n = 3 biologically independent samples in each group). d H&E staining images of skin tissue after subcutaneous embedding of d-SMGs in SD rat skin incision model (n = 3 biologically independent samples in each group). Data are presented as mean values ± SEM. Scale bar, 1 mm (images in d). Source data are provided as a Source data file.