. 2022 Jan 22;37(2):313–319. doi: 10.1038/s41433-022-01937-3

Table 2.

Central retinal thickness (oedema), vessel density (capillary closure) and ganglion cell and inner plexiform layers thinning (neurodegeneration) comparison between T2D individuals that worsened 1- or 2-steps in DRSS stage vs the ones that improved or did not change, at the end of the follow-up period.

		CRT [µm]		VD (Inner Ring SCP) [mm⁻¹]		GCL + IPL Thinning [µm]
		V1	V4-V1	V1	V4-V1	V1	V4-V1
Worsening (1- or 2-step) (n = 10)	Avg	254.5	1.6	21.5	−1.2	82.3	−0.7
Worsening (1- or 2-step) (n = 10)	SD	26.9	3.6	0.9	1.0	9.0	1.2
No Change + Improving (n = 64)	Avg	272.0	1.7	21.2	−0.4	79.1	−1.4
No Change + Improving (n = 64)	SD	25.4	17.5	1.3	1.0	8.3	5.2
Statistical Diff. V4-V1 (p value)^a			0.61		0.03		0.94

CRT central retinal thickness, VD vessel density, SCP superficial capillary plexus, GPL + IPL ganglion cell layer and inner plexiform layer.

^aMann-Whitney U-test for comparison between DRSS stage worsening (1- or 2- step) and improving or no change patients. Bold value represents statistical significance (p < 0.05).