Table 2.

Visual acuity and spherical equivalent by mutation type in RP2 carrier females and affected males.

Mutation	Carrier females			Affected males			Visual acuity p-value	Spherical equivalent p-value
	N	LogMAR VA [mean (median, range)]	Spherical Equivalent [D] [mean (median, range)]	N	LogMAR VA [mean (median, range)]	Spherical Equivalent [D] [mean (median, range)]
Missense Mutation	9	0.4 (0.5, 0.1 to 1)	−4.4 (−4.5, 2.8 to −14.5)	9	1.4 (1.3, 0.5 to 2.7)	−6.5 (−6.6, −2 to −9.6)	0.001	0.38
Nonsense Mutation	11	0.4 (0.5, 0 to 1.9)	−4.5 (−5.0, 0.3 to −15.3)	8	1.2 (1.0, 0.2 to 2.7)	−1.8 (−3.4, 2.8 to −4.5)	0.02	0.28
Deletion Mutation	1	0.2 (0.2, NA)	0.8 (0.8, NA)	3	1.6 (1.6, 1.4 to 1.7)	−12.8 (−12.5, −12 to −13.9)	—	—
Frameshift Mutation	1	1.0 (1.0, NA)	4.3 (4.3, NA)	2	1.1 (1.1, 0.5 to 1.8)	−6.7 (−6.7, −0.9 to −12.5)	—	—
Splice Mutation	1	0.2 (0.2, NA)	−1.3 (−1.3, NA)	1	0.5 (0.5, NA)	−2.5 (−2.5, NA)	—	—