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. Author manuscript; available in PMC: 2024 Apr 1.
Published in final edited form as: Anesth Analg. 2022 Jul 25;136(4):779–788. doi: 10.1213/ANE.0000000000006146

Figure 2. Ketamine induces delirium-like behavior and increases serum total tau amounts in mice.

Figure 2.

A: Composite Z-scores 1 h after ketamine administration, n = 12 in each group. B: Composite Z-scores 2 h after ketamine administration, n = 12 in each group. C: Serum total tau protein concentration 1 h after ketamine administration, n = 11 in CON group, n = 12 in KET group. D: Serum total tau protein concentration 2 h after ketamine administration, n = 6 in each group. E: Serum total tau protein concentration 6 h after ketamine administration, n = 6 in each group. Mann-Whitney test was applied to analyze data in panels A and B. Grubbs’ test was applied to identify an outlier owing to hemolysis in data in panel C. Student’s t-test was applied to analyze data in panels C, D, and E. Error bars represent 25%–75% interquartile range in panels A and B, and SD in panels C, D, and E; * indicates P < 0.05 by statistical analysis; ns indicates no significant difference between groups (P > 0.05) by statistical analysis.