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. 2023 Jan 11;13:1085309. doi: 10.3389/fphar.2022.1085309

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Copyright © 2023 Lai, Yang, zhang, Zhuang, Ma, Lin, Zeng and Yin.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Reversal effect of Zvad on AC-induced apoptosis of hepatocytes. (A, B) Reversal effect of Zvad on AC-induced apoptosis of SMMC7721. (C, D) Reversal effect of Zvad on AC-induced apoptosis of BEL-7402. (E, F) Reversal effect of Zvad on AC-induced apoptosis of TUNEL in SMMC7721. (G, H) Reversal effect of Zvad on AC-induced apoptosis of TUNEL in BEL-7402. The image of confocal, and apoptotic cells was stained by ALEX647 (red), and the nuclei were dyed blue by DAPI. *p < 0.05; **p < 0.01; ***p < 0.001 (vs. 0 group).