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. 2022 Nov 5:10.1111/febs.16662. Online ahead of print. doi: 10.1111/febs.16662

Fig. 2.

Fig. 2

The component antibodies of Evusheld simultaneously bind to separate regions of the RBD of the SARS‐CoV‐2 S protein (blue) [Protein Data Bank (PDB) ID: 7L7E, visualized with ucsf chimerax, version 1.4] [21, 22]. Tixagevimab consists of a heavy chain (green) and a light chain (orange) that form an aromatic cage. Cilgavimab consists of a heavy chain (pink) that is able to interact with the RBD and a light chain (teal). Hydrogen bonds between each of the antibodies and the RBD are represented by dotted cyan lines.