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. 2022 Nov 5:10.1111/febs.16662. Online ahead of print. doi: 10.1111/febs.16662

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© 2022 Federation of European Biochemical Societies.

This article is being made freely available through PubMed Central as part of the COVID-19 public health emergency response. It can be used for unrestricted research re-use and analysis in any form or by any means with acknowledgement of the original source, for the duration of the public health emergency.

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Fig. 8 — Chemical structure of chloroquine, an aminoquinoline that increases the pH of endosomes. Chloroquine has been used to treat malaria, viral diseases, and autoimmune diseases and was investigated for use against SARS‐CoV‐2 by preventing endosomal entry in the early stages of the pandemic [8, 74].