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. 2022 Nov 5:10.1111/febs.16662. Online ahead of print. doi: 10.1111/febs.16662

Table 2.

Summary of recommendations for viral replication targeted antivirals. A list of all of the antivirals discussed in the viral replication section is provided, as well as an indication of when in the progression of the disease they are recommended. Note that no antivirals are recommended as preventative treatment (before one is infected); the majority are recommended for mild to moderate infection, only one is recommended for individuals who might develop severe infection, and three are not currently authorized for COVID‐19 treatment.

Antiviral Timing of treatment References
Paxlovid Mild to moderate infection [76, 77]
Kaletra Not authorized for COVID‐19 treatment [78]
Remdesivir Infection with high risk to develop severe infection [79]
Ribavirin Not authorized for COVID‐19 treatment [48, 49]
Favipiravir Not authorized for COVID‐19 treatment [80]
Molnupiravir Mild to moderate infection [81]