Table 4.
Cox Proportional Hazards Model Results of Post Transplant Survival, January 2005 – June 2019
95% Confidence Interval | ||||
---|---|---|---|---|
Predictor | Hazard Ratio | Lower | Upper | p-value |
HIV positive recipient | 0.94 | 0.53 | 1.65 | 0.820 |
Donor age (per 5 years) | 1.06 | 1.05 | 1.07 | <0.001 |
Recipient age | ||||
<45 (per 5 years) | 0.91 | 0.89 | 0.93 | <0.001 |
>45 (per 5 years) | 1.20 | 1.16 | 1.24 | <0.001 |
Recipient male sex | 0.96 | 0.91 | 1.02 | 0.181 |
Recipient ethnicity (reference: White) | ||||
Black | 1.32 | 1.24 | 1.40 | <0.001 |
Hispanic | 1.00 | 0.91 | 1.10 | 0.995 |
Other | 0.96 | 0.85 | 1.09 | 0.550 |
Donor/recipient sex mismatch | 1.05 | 0.98 | 1.13 | 0.147 |
Recipient heart failure etiology (reference: ischemic) | ||||
Non-ischemic dilated | 0.79 | 0.75 | 0.84 | <0.001 |
Other | 0.98 | 0.89 | 1.02 | 0.13 |
Recipient diabetes | 1.27 | 1.20 | 1.33 | <0.001 |
Recipient durable LVAD support | 1.07 | 1.01 | 1.14 | 0.016 |
Recipient ECMO support | 1.95 | 1.61 | 2.37 | <0.001 |
Recipient temporary VAD support | 1.21 | 1.00 | 1.45 | 0.048 |
Recipient IABP support | 1.06 | 0.98 | 1.16 | 0.161 |
Recipient prior cardiac surgery | 1.13 | 1.07 | 1.19 | <0.001 |
Graft ischemic time (per hour) | 1.08 | 1.06 | 1.11 | <0.001 |
Transplant era (reference: 2005–2009) | ||||
2010–2014 | 0.85 | 0.78 | 0.88 | <0.001 |
2015–2019 | 0.82 | 0.77 | 0.89 | <0.001 |
Transplant center annualized volume | ||||
<20 (per 5 transplants) | 0.93 | 0.90 | 0.96 | <0.001 |
>20 (per 5 transplants) | 1.07 | 1.04 | 1.11 | <0.001 |
LVAD, left ventricular assist device; ECMO, extracorporeal membrane oxygenation; VAD, ventricular assist device; IABP, intra-aortic balloon pump |