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. 2001 Oct;69(10):6179–6185. doi: 10.1128/IAI.69.10.6179-6185.2001

TABLE 6.

Mouse competition assay with CFT073 and its isogenic iron utilization strains

CFT073 vs.: No. of mice Competitive indexa
Bladders Kidneys
CFT073-ENT/IUC 6b 0.90 ± 0.38c 1.11 ± 0.52c
CFT073-IUT 7d 0.008 ± 0.06e 0
CFT073-LH 7d 0.026 ± 0.003e 0.058 ± 0.006c
a

Competitive index is the ratio of output mutant to wild-type bacteria (recovered from the bladder or kidney) divided by the ratio of input mutant to wild-type bacteria (inoculated into the mouse). A competitive index of <1 indicates that the strain was recovered in lower numbers relative to the wild type. 

b

Bacteria were not recovered from the kidneys of two of the mice. 

c

P ≥ 0.1. 

d

Bacteria were not recovered from the kidneys of one of the mice. 

e

P < .001.