Figure 3.

Correlations between the spermatogonial numbers and the blood serum hormone values of transwomen. Spermatogonia per mm³ were correlated with levels of (A) follicle-stimulating hormone (FSH) (n  = 23), (B) luteinizing hormone (LH) (n  = 22), (C) testosterone (n  = 24), (D) estradiol (n  = 24), (E) prolactin (n  = 23) and (F) free testosterone (n  = 24). Spearman's rank correlation coefficient analysis was performed and revealed significant correlations for LH and estradiol. The blue lines mark the male reference values and the red lines mark the female reference values. Clinic A (n  = 5) stopped the gender-affirming hormone therapy 4–6 weeks prior to the surgery, clinic B (n = 16) stopped the hormone therapy 2 weeks prior to the surgery, while clinic C (n = 4) continued the therapy until the day of GAS.