. 2023 Jan 19;12(1):e220161. doi: 10.1530/ETJ-22-0161
This work is licensed under a Table 1.
Clinical and pathological characteristics and pre-surgical CEA and Ct values of the enrolled series.
| Group | Overall | Sporadic MTC | Hereditary MTC | |
|---|---|---|---|---|
| n (%)a | 90 | 51 | 39 | |
| T (%) | 1 | 48 (64.0) | 29 (63.0) | 19 (65.5) |
| 2 | 11 (14.7) | 7 (15.2) | 4 (13.8) | |
| 3 | 14 (18.7) | 8 (17.4) | 6 (20.7) | |
| 4 | 2 (2.6) | 2 (4.4) | 0 (0) | |
| NA | 15 | 5 | 10 | |
| n (%) | 0 | 43 (55.8) | 26 (54.2) | 17 (58.6) |
| 1 | 29 (37.7) | 19 (39.6) | 10 (34.5) | |
| X | 5 (6.5) | 3 (6.2) | 2 (6.9) | |
| NA | 13 | 3 | 10 | |
| M (%) | 0 | 57 (81.4) | 33 (78.6) | 24 (85.7) |
| 1 | 6 (8.6) | 5 (11.9) | 1 (3.6) | |
| X | 7 (10.0) | 4 (9.5) | 3 (10.7) | |
| NA | 20 | 9 | 11 | |
| Stage (%) | I | 33 (47.1) | 19 (46.3) | 14 (48.3) |
| II | 8 (11.4) | 4 (9.8) | 4 (13.8) | |
| III | 9 (12.9) | 6 (14.6) | 3 (10.3) | |
| IV | 20 (28.6) | 12 (29.3) | 8 (27.6) | |
| NA | 20 | 10 | 10 | |
| Cancer size (mm), median value (IQR); mean (SD) | 10.00 (1.00–18.5); 14.63 (1.77) |
12.00 (8.00–20.00); 17.12 (2.50) |
6.5 (3–15); 10.69 (2.14) |
|
| Pre-surgical CEA level (ng/mL), median value (IQR); mean (SD) | 13.00 (4.70–50.9); 33.88 (7.65) |
13.00 (6.87); 29.36 (6.87) |
46.20 (3.95–115.75); 59.85 (34–21) |
|
| Pre-surgical Ct level (ng/L), median value (IQR); mean (SD) | 127.00 (44.10–761.25); 1760.01 (620.85) |
134.00 (58.98– 1096.25); 1667.44 (574.27) | 115.00 (33.38– 683.25); 1911.82 (1361.28) |
aPercentages calculated based on available data.
CEA, carcinoembryonic antigen; Ct, calcitonin; IQR, interquartile range; MTC, medullary thyroid cancer; SD, standard deviation.