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. 2023 Jan 24;137(2):163–180. doi: 10.1042/CS20220525

Figure 6. The cf-DNA of atherosclerosis patients.

Figure 6

(A) The cfDNA copy number in normal subject (Plaque [-]) and subjects with carotid plaques. *P<0.05, **P<0.01 compared with Plaque (-). Closed circles represent current smokers. (B) Comparison of mt-cfDNA and n-cfDNA among four groups. *P<0.05, **P<0.01 compared with Plaque (-). (C) Correlation of cfDNA copy number with plaque thickness. (D) ROC analysis for atherosclerosis incidence (plaque [-] vs. plaque[+]), using mt-cfDNA and n-cfDNA. Abbreviations: AUC, area under the curve; mt-cfDNA, mitochondrial cell-free DNA; n-cfDNA, nuclear cell-free DNA.