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. 2023 Jan 11;13:1088243. doi: 10.3389/fmicb.2022.1088243

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Copyright © 2023 Bi, Wang and Xia.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Conservative analysis of antigen epitope. (A) Phylogenetic relationships based on the H genes of 405 canine distemper virus (CDV) strains. Distance values were calculated by the Clustal W program using the MEGA 6.0 software package. The tree was constructed by the Maximum-Likelihood method, and bootstrap values were calculated on 1,000 replicates. (B) Alignment of amino acids sequence of the neutralizing epitope in different lineages of CDV strains. The dots indicated the same amino acids with the epitope 238DIEREFD244 in red box.