Table 1.
Characteristics of CDB pathology-confirmed CIN2 and CIN3.
| Characteristics | CIN2 CBD (n = 100) | CIN3 CBD (n = 118) | ||||
|---|---|---|---|---|---|---|
| Frequency | Percent | Frequency | Percent | |||
| Age median (IQR) | 40 (35.2-50.0) | 40 (35.5-51.0) | ||||
| Cytology | ||||||
| LSIL-* | 79 | 79.0 | 69 | 58.5 | ||
| ASC-H+^ | 21 | 21.0 | 49 | 41.5 | ||
| HR-HPV genotype | ||||||
| HPV16/18(+) | 34 | 34.0 | 68 | 57.6 | ||
| Other 12 HR-HPV(+) | 59 | 59.0 | 44 | 37.3 | ||
| Negative | 7 | 7.0 | 6 | 5.1 | ||
| CKC pathology | ||||||
| Cervicitis | 8 | 8.0 | 4 | 3.4 | ||
| CIN1 | 22 | 22.0 | 2 | 1.7 | ||
| CIN2 | 34 | 34.0 | 19 | 16.1 | ||
| CIN3 | 36 | 36.0 | 70 | 59.3 | ||
| ESCC | – | – | 23 | 19.5 | ||
| Margin status | ||||||
| Negative | 98 | 98.0 | 90 | 76.3 | ||
| Positive | 2 | 2.0 | 28 | 23.7 | ||
*including negative for intraepithelial lesion or malignancy (NILM), atypical squamous cells of undetermined significance (ASCUS), and low-grade squamous intraepithelial lesion (LSIL); ^including: atypical squamous cells cannot exclude HSIL(ASC-H),atypical glandular cell(AGC), and high-grade squamous intraepithelial lesion(HSIL). CKC, cold knife conization; CIN, cervical intraepithelial neoplasia; ESCC, early-stage cervical cancer; IQR, inter quartile range.