Table 2.
PAX1m levels stratified by low-, medium-, and high-risks of CIN2+, CIN3+ and ESCC.
| Variable | OR/Adjusted OR (95%CI) a | P for trend b | ||
|---|---|---|---|---|
| PAX1 m | Low N = 93 |
Moderate N = 51 |
High N = 74 |
|
| Median (range) | 20.4 (16.3-22.3) | 10.6 (9.11-14.35) | 6.4 (1.1-9.0) | |
| OR, CIN2+ | 1.0 | 1.43 (0.62-3.28) | 12.52 (2.85-55.00) | <0.001 |
| P | 0.404 | 0.001 | ||
| OR, CIN3+ | 1.0 | 2.21 (1.10-4.44) | 20.61 (8.08-52.57) | <0.001 |
| P | 0.025 | <0.001 | ||
| OR, ESCC | 1.0 | 3.76 (0.33-42.46) | 34.07 (4.45-261.08) | <0.001 |
| P | 0.285 | 0.001 | ||
| PAX1m Model 1 c | ||||
| OR, CIN2+ | 1.0 | 1.36 (0.58-3.18) | 11.98 (2.68-53.65) | <0.001 |
| P | 0.473 | 0.001 | ||
| OR, CIN3+ | 1.0 | 2.00 (0.98-4.08) | 19.27 (7.39-50.22) | <0.001 |
| P | 0.056 | <0.001 | ||
| OR, ESCC | 1.0 | 3.20 (0.27-37.08) | 24.85 (3.17-194.67) | <0.001 |
| P | 0.353 | 0.002 | ||
a ORs and 95%CI were calculated with the use of the logistic regression.
b P for trend, from a 1 degree-of-freedom trend test.
c The following variables were included to control for the effects of PAX1m: hrHPV [other hrHPV (+) except HPV16/18, HPV16/18 (+)] and cytology (<LSIL, LSIL+).