TABLE 2.

Comparison of ADC histogram parameters and minimum ADC and mean ADC between IDHmut/MGMTmet and the other glioma group.

Variable#	IDHmut/MGMTmet, N = 40	Other molecular status (IDHwt/MGMTmet, n = 32; IDHmut/MGMTunmet, n = 1; IDHwt/MGMTunmet, n = 45), N = 78	P-value
ADC histogram parameters
10th percentile	1022.81 ± 152.53	803.55 ± 134.00	<0.001*
90th percentile	1451.00 (1309.00, 1679.75)	1273.50 (1135.00, 1439.28)	<0.001*
Entropy	4.89 (4.55, 5.14)	4.82 (4.57, 5.15)	0.695
Interquartile range	237.84 ± 79.60	232.37 ± 84.94	0.736
Kurtosis	3.89 (3.24, 4.65)	4.63 (3.66, 6.95)	0.003*
Maximum	2251.84 ± 508.33	2231.36 ± 532.18	0.841
Mean absolute deviation	147.18 ± 46.96	146.89 ± 51.14	0.976
Mean	1248.80 ± 165.37	1023.07 ± 171.02	<0.001*
Median	1238.63 ± 177.84	1002.16 ± 170.87	<0.001*
Minimum	556.75 ± 228.17	432.44 ± 186.38	0.002*
Range	1695.09 ± 664.53	1798.92 ± 604.99	0.395
Robust mean absolute deviation	99.81 ± 32.83	97.81 ± 35.11	0.766
Root mean squared	1264.64 ± 164.74	1042.41 ± 175.67	<0.001*
Skewness	0.30 ± 0.66	0.89 ± 0.68	<0.001*
Uniformity	0.040 (0.035, 0.051)	0.043 (0.036, 0.051)	0.481
Variance	36408.81 (20943.50, 53342.96)	34819.11 (22237.20, 57707.43)	0.887
Direct ADC measurements
Minimum ADC	971.63 ± 226.79	719.32 ± 162.30	<0.001*
Mean ADC	1146.96 ± 218.15	870.15 ± 157.31	<0.001*

^#Continuous variables with normal distribution were described as mean and standard deviations, and continuous variables with skewed distribution were described as median and quartiles. *P < 0.05.