Figure 7.

YUM70 in combination with cisplatin reduces clonogenic capacity of cisplatin-resistant SCC15 cells. (A) CisR-3 cells or parental SCC15 cells were treated with the indicated dosages of cisplatin alone or in combination with 2.5 μM of YUM70, with DMSO serving as vehicle control, for 48 hr. Colonies formed after 12 days post-treatment were stained with crystal violet and counted. (B) Quantitative results of (A). Data are presented as means ± S.D. (n=3). *P ≤ 0.05, **P ≤ 0.01 (Student’s t test).