TABLE 1.

Significant relationships between the position of the longest intron and gene biological functions based on GSEA.

Absolute position of the longest intron
GO Term/p-value	Intron 1	Intron 2	Intron 3	Intron 4	Intron 5	Intron 6	Intron 7	Intron 8	Intron 9
cell death	1.8E-04	1.6E-09	ns	ns	ns	ns	ns	ns	ns
programmed cell death	4.0E-04	4.9E-08	ns	ns	ns	ns	ns	ns	ns
apoptotic process	5.0E-04	2.2E-07	ns	ns	ns	ns	ns	ns	ns
regulation of cell death	Ns	2.6E-04	ns	ns	ns	ns	ns	ns	na
regulation of hydrolase activity	Ns	8.1E-04	ns	ns	ns	ns	ns	ns	ns
Relative position of the longest intron
GO Term/p-value			(0; .33]		(.33; .66]		(.66; 1]
reproductive process			ns		1.5E-04		ns
Reproduction			ns		1.8E-04		ns
DNA duplex unwinding			ns		1.3E-02		ns
DNA repair			ns		ns		1.4E-05
DNA metabolic process			ns		ns		5.3E-05
cellular response to DNA damage stimulus			ns		ns		1.2E-04
mitotic rekombination			na		ns		2.3E-04
telomere maintenance			ns		ns		2.9E-04
double-strand break repair			ns		ns		6.0E-04
telomere organization			ns		ns		2.0E-03
regulation of interleukin-1 production			ns		ns		1.7E-02
interleukin-1 production			ns		ns		1.7E-02
telomere maintenance via recombination			na		na		1.8E-02

na, not available; ns, not significant; GO, gene ontology; GSEA, gene set enrichment analysis.