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Virulence of CP9 (wt) and CP197 (ireA) in a mouse UTI model
| Result | No. positive in bladder (n = 20)
|
No. positive in urine (n = 14a)
|
||
|---|---|---|---|---|
| CP9 | CP197 | CP9 | CP197 | |
| Any CFU in broth | 20 | 20 | 7b | 4b |
| Any CFU on plates | 20 | 17 | 13 | 12 |
| >1 × other strain | 10 | 10 | 9 | 5 |
| >15 × other strain | 7c | 0c | 6 | 3 |
Postmortem urine was available from 14 of 20 mice.
Broth urine cultures were done for 8 of 14 urine samples.
For CP9 versus CP197, the P value was 0.02 (McNemar's test).
