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. 2023 Jan 25;160:2. doi: 10.1186/s41065-023-00265-0

Table 3.

KEGG analysis result of 22 enriched pathways

ID Description Gene Ratio Bg Ratio p.adjust FDR Rich Factor a
hsa04060 Cytokine-cytokine receptor interaction 34/155 295/8108 < 0.001 < 0.001 0.115
hsa04061 Viral protein interaction with cytokine and cytokine receptor 19/155 100/8108 < 0.001 < 0.001 0.190
hsa05340 Primary immunodeficiency 12/155 38/8108 < 0.001 < 0.001 0.316
hsa05332 Graft-versus-host disease 12/155 42/8108 < 0.001 < 0.001 0.286
hsa04659 Th17 cell differentiation 16/155 107/8108 < 0.001 < 0.001 0.149
hsa04612 Antigen processing and presentation 14/155 78/8108 < 0.001 < 0.001 0.179
hsa04650 Natural killer cell mediated cytotoxicity 16/155 131/8108 < 0.001 < 0.001 0.122
hsa04062 Chemokine signaling pathway 18/155 192/8108 < 0.001 < 0.001 0.094
hsa05321 Inflammatory bowel disease 11/155 65/8108 < 0.001 < 0.001 0.169
hsa04640 Hematopoietic cell lineage 12/155 99/8108 < 0.001 < 0.001 0.121
hsa04658 Th1 and Th2 cell differentiation 11/155 92/8108 < 0.001 < 0.001 0.119
hsa04514 Cell adhesion molecules 13/155 149/8108 < 0.001 < 0.001 0.087
hsa04660 T cell receptor signaling pathway 10/155 104/8108 < 0.001 < 0.001 0.096
hsa05235 PD-L1 expression and PD-1 checkpoint pathway in cancer 9/155 89/8108 < 0.001 < 0.001 0.101
hsa05320 Autoimmune thyroid disease 7/155 53/8108 < 0.001 < 0.001 0.132
hsa05330 Allograft rejection 6/155 38/8108 < 0.001 < 0.001 0.158
hsa04940 Type I diabetes mellitus 6/155 43/8108 0.002 0.001 0.139
hsa05323 Rheumatoid arthritis 8/155 93/8108 0.004 0.003 0.086
hsa05143 African trypanosomiasis 5/155 37/8108 0.006 0.006 0.135
hsa04672 Intestinal immune network for IgA production 5/155 49/8108 0.022 0.019 0.102
hsa04630 JAK-STAT signaling pathway 9/155 162/8108 0.034 0.030 0.056
hsa05416 Viral myocarditis 5/155 60/8108 0.049 0.043 0.083

a Rich Factor = countsofDEGsenrichedinonepathwaycountsofallthegenesrelatedinonepathway