Table 1.
Radiomic features significantly correlated with characteristics of CD8+ T cell exhaustion selected through LASSO regression
| CT | PET | |||
|---|---|---|---|---|
| Feature | Coefficient | Feature | Coefficient | |
| Early Tex proportion among CD8+ T cells | SurfaceAreaDensity | 0.291541 | Contrast | 0.003785638 |
| Homogeneity2 | -3.455633658 | |||
|
Kurtosis (Intensity Histogram) |
1.696675694 | |||
| Kurtosis (Intensity Direct) | -0.482919952 | |||
| Terminal Tex proportion among CD8+ T cells | / | / | InverseVariance | -124.62754 |
| E/T | / | / | Homogeneity2 | -1.09342672 |
|
Kurtosis (Intensity Histogram) |
0.26680888 | |||
| Kurtosis (Intensity Direct) | -0.02380306 | |||
| MFI of PD-1 expression on CD8+ T cells | Compactness2 | 1069.80865 | InverseVariance | -2068.013 |
| ConvexHullVolume3D | -32.8878 | |||
Tex exhausted T cells
E/T the ratio of early to terminal Tex
MFI mean fluorescence intensity