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In vitro cytotoxicity and apoptosis analysis. a Viability assay in HepG2 and Huh-7 cells after treating them with free drug (apigenin), different experimental formulations (NLCs, PEG-NLCs, and Apt-NLCs), and AS1411 functionalized blank liposomes for 48 h with drug concentration range (10-100 µM) respectively. b FACS analysis of cellular apoptosis applying Annexin V-FITC staining in HepG2 cells treated with NLCs, PEG-NLCs, and Apt-NLCs with their equivalent IC50 doses of the drug at 48 h
