Table 2.
Hardy-Weinberg equilibrium analysis of 20 SNPs in all groups
| Gene | SNP ID | Position | P value | ||
|---|---|---|---|---|---|
| Control (N = 464) |
MDD (N = 439) |
BPD (N = 600) |
|||
| LEPR | rs1137101 | chr1:65592830 | 0.330 | 0.999 | 0.430 |
| SCN2A | rs17183814 | chr2:165295879 | 0.829 | 0.510 | 0.999 |
| SCN1A | rs2298771 | chr2:166036278 | 0.768 | 0.188 | 0.803 |
| SCN1A | rs3812718 | chr2:166053034 | 0.699 | 0.620 | 0.307 |
| UGT1A9 | rs2741049 | chr2:233673188 | 0.509 | 0.082 | 0.412 |
| GSK3B | rs334558 | chr3:120094435 | 0.999 | 0.999 | 0.728 |
| HLA-B | rs2442736 | chr6:31378844 | 0.615 | 0.999 | 0.642 |
| ABCB1 | rs1045642 | chr7:87509329 | 0.059 | 0.605 | 0.335 |
| NAT2 | rs1041983 | chr8:18400285 | 0.707 | 0.209 | 0.805 |
| NAT2 | rs1801280 | chr8:18400344 | 0.065 | 0.606 | 0.241 |
| NAT2 | rs1799929 | chr8:18400484 | 0.144 | 0.063 | 0.257 |
| NAT2 | rs1799930 | chr8:18400593 | 0.526 | 0.224 | 0.217 |
| NAT2 | rs1208 | chr8:18400806 | 0.354 | 0.239 | 0.257 |
| CYP2C19 | rs12248560 | chr10:94761900 | 0.999 | 0.999 | 0.999 |
| CYP2C19 | rs4986893 | chr10:94780653 | 0.999 | 0.373 | 0.402 |
| CYP2C19 | rs4244285 | chr10:94781859 | 0.123 | 0.648 | 0.999 |
| CYP2C9 | rs1057910 | chr10:94981296 | 0.999 | 0.999 | 0.999 |
| ANKK1 | rs1800497 | chr11:113400106 | 0.104 | 0.377 | 0.867 |
| SH2B1 | rs3888190 | chr16:28878165 | 0.188 | 0.156 | 0.082 |
| INSR | rs2396185 | chr19:7246650 | 0.054 | 0.545 | 0.576 |
The GRCh38 human reference genome was used for genetic variant location