Table 5.

Fetal outcomes in ART. Pa, comparisons among three groups. Pb, comparison between ART and planned pregnancy. Pc, comparison between ART and unplanned pregnancy. Pd, comparison between planned and unplanned pregnancy

	ART (n = 65)	Planned (n = 201)	Unplanned (n = 23)	Pa	Pb	Pc	Pd
Outcomes
Time of delivery, weeks, mean ± SD	36.8 ± 2.1	37.1 ± 2.0	34.8 ± 3.1	< 0.001	0.267	0.001	< 0.001
Birth weight, mean ± SD	2653.5 ± 578.6	2703.3 ± 491.3	2298.3 ± 762.5	0.003	0.498	0.023	0.001
IUGR, n (%)	5 (7.7)	17 (8.5)	4 (17.4)	0.383
Fetal distress, n (%)	5 (7.7)	32 (15.9)	3 (13.0)	0.233
LBW infants, n (%)	20 (30.8)	51 (25.4)	7 (30.4)	0.641
VLBW infants, n (%)	2 (3.1)	5 (2.5)	5 (21.7)	0.001	0.680	0.012	0.001
Neonatal hypoglycemia, n (%)	2 (3.1)	2 (1.0)	1 (4.3)	0.188
Neonatal pneumonia, n (%)	3 (4.6)	3 (1.5)	1 (4.3)	0.702
NRDS, n (%)	5 (7.7)	7 (3.5)	1 (4.3)	0.621
Neonatal pathological jaundice, n (%)	11 (16.9)	29 (14.4)	2 (8.7)	0.702
Malformation, n (%)	6 (9.2)	12 (6.0)	1 (4.3)	0.621
PDA, n (%)	2 (3.1)	9 (4.5)	2 (8.7)	0.501
PFO, n (%)	7 (10.8)	24 (11.9)	1 (4.3)	0.707
ASD, n (%)	4 (6.2)	5 (2.5)	1 (4.3)	0.280
Transfer to ICU, n (%)	10 (15.4)	70 (34.8)	8 (34.8)	0.011	0.003	0.070	1.000
Laboratory tests
ANA, n (%)	12 (18.5)	24 (11.9)	4 (17.4)	0.313
Anti-dsDNA, n (%)	5 (7.7)	11 (5.5)	3 (13.0)	0.244
Anti-SSA, n (%)	6 (9.2)	12 (6.0)	3 (13.0)	0.265
Anti-SSB, n (%)	2 (3.1)	0 (0)	1 (4.3)	0.028	0.059	1.000	0.103

Abbreviation: ART Assisted reproductive therapy, ASD Atrial septal defect, ICU Intensive care unit, LBW Low-birth-weight, IUGR Intrauterine growth retardation, NRDS Neonatal respiratory distress syndrome, PDA Patent ductus arteriosus, PFO Patent foramen ovale, SD Standard deviation, VLBW Very-low-birth-weight