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. 2023 Jan 24;21:44. doi: 10.1186/s12967-022-03840-7

Fig. 2.

Fig. 2

Flow diagram of study. First a, positive and negative samples are immunohistochemically distinguished, and tumor regions and radiomic features are extracted using the deep learning model. Second b, radiomics features are combined with gene expression data, and the biological functions of radiomic features are inferred by enrichment analysis. Third c, auxiliary features are identified based on Simpson index, and machine learning models are constructed