Table 1 –
Clinicopathologic Characteristics of SETD2-Mutated Colorectal Carcinoma
| Total Number | 24 | 100% |
|---|---|---|
| Age | ||
| Median, IQR | 62.4 | [49.1–73.6] |
| Sex | ||
| Male | 11 | 46% |
| Female | 13 | 54% |
| Race | ||
| White | 17 | 71% |
| Black | 5 | 21% |
| Asian | 1 | 4% |
| Declined | 1 | 4% |
| Ethnicity | ||
| Non-Hispanic | 21 | 88% |
| Hispanic | 1 | 4% |
| Declined | 1 | 4% |
| Tumor Location | ||
| Proximal Colon | 12 | 50% |
| Cecum | 3 | 13% |
| Ascending | 6 | 25% |
| Transverse | 3 | 13% |
| Distal Colon | 12 | 50% |
| Descending | 2 | 8% |
| Sigmoid | 5 | 21% |
| Rectum | 5 | 21% |
| Tumor Stage | ||
| I | 1 | 4% |
| II | 10 | 42% |
| III | 7 | 29% |
| IV | 6 | 25% |
| Size | ||
| Median, IQR | 5.9 | [4–8] |
| Tumor Grade | ||
| Unknown | 2 | 8% |
| Low/Mod | 16 | 67% |
| High | 6 | 25% |
| Tumor Stage | ||
| Unknown | 3 | 13% |
| pT1 | 1 | 4% |
| pT2 | 3 | 13% |
| pT3 | 11 | 46% |
| pT4 | 6 | 25% |
| Lymph Node | ||
| pNX | 4 | 17% |
| pN0 | 9 | 38% |
| pN1 | 4 | 17% |
| pN2 | 7 | 29% |
| Metastases | ||
| pMX | 15 | 63% |
| pM0 | 3 | 13% |
| pM1 | 6 | 25% |
| Histology Subtypes | ||
| Adenocarcinoma, NOS | 22 | 92% |
| Mucinous | 2 | 8% |
| Microsatellite Status | ||
| Stable | 20 | 83% |
| Unstable | 4 | 17% |