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. Author manuscript; available in PMC: 2023 Jan 25.
Published in final edited form as: Circ Genom Precis Med. 2019 Oct 22;12(11):e002723. doi: 10.1161/CIRCGEN.119.002723

Table 3.

Mean Yield and NCIC Compared Between Various Study Methodologies

Yield, % NCIC
Direct contact 46.38 2.06
Indirect contact 43.17 0.86
Beyond FDR 39.8 3.65
FDR only 54.5 0.80
Active sample collection 33.5 4.11
Centralized collection 47.45 1.06
Genetic testing 44.3 2.47
Biochemical testing 45.2 0.42

FDR indicates first-degree relative; and NCIC, new cases per index case.