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. 2023 Jan 9;13:1073232. doi: 10.3389/fgene.2022.1073232

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Copyright © 2023 Zhang, Wang, Fu, Gao, Yang, Lei, Shi, Le, Xiong, Liu, Zhang, Su, Chen, Liu and Niu.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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The epithelial cell type classifications in PNI-PCa tumor tissue. (A) Epithelial cells are divided into 13 different subgroups, UMAP of epithelial cells annotated by cell types. (B) Violin plots of marker genes across the epithelial cell subtypes. (C) The relative expression of FOLH1, KLK3, EGR1, PIGR, AGR2, and MMP7 genes in different epithelial subgroups. (D) GO enrichment analysis for DEGs in basal/intermediate cell subtype C5 and luminal cell subtype C13, respectively.