Table 2.
Variable | No. (%) | P | |
---|---|---|---|
| |||
PD with psychotic symptoms (n=63) | PD without psychotic symptoms (n=273) | ||
Age at PD diagnosis (yr)* | 66.24±9.83 | 66.13±10.77 | 0.982† |
| |||
Gender | |||
| |||
Men | 41 (65.1) | 158 (57.9) | 0.294‡ |
| |||
Women | 22 (34.9) | 115 (42.1) | |
| |||
Ethnicity | |||
| |||
Chinese | 56 (88.9) | 232 (85.0) | 0.424‡ |
| |||
Malay/Indian/other | 7 (11.1) | 41 (15.0) | |
| |||
Years of education* | 7.60±4.45 | 7.37±5.43 | 0.617† |
| |||
Duration of follow-up at first onset of psychosis (yr)* | 3.81±1.95 | ||
| |||
MMSE§ | |||
| |||
MMSE <25 | 22 (34.9) | ||
| |||
MMSE ≥25 | 32 (50.8) | ||
| |||
Missing | 9 (14.3) | ||
| |||
H&Y stage | |||
| |||
Stage 1 | 1 (1.6) | ||
| |||
Stage 2 | 28 (44.4) | ||
| |||
Stage 3 | 7 (11.1) | ||
| |||
Stage 4 | 10 (15.9) | ||
| |||
Stage 5 | 5 (7.9) | ||
| |||
MMSE score per calendar year* | |||
| |||
2006 | 26.18±3.34 | 25.58±3.16 | <0.001¶ |
| |||
2007 | 24.74±5.37 | 24.92±4.36 | |
| |||
2008 | 24.51±4.09 | 24.84±4.29 | |
| |||
2009 | 22.66±5.76 | 24.17±5.64 | |
| |||
2010 | 23.83±6.01 | 25.18±3.32 | |
| |||
2011 | 23.64±4.45 | 24.44±4.18 | |
| |||
2012 | 24.93±4.92 | 24.83±4.77 | |
| |||
2013 | 21.70±6.03 | 23.39±4.83 | |
| |||
H&Y staging per calendar year* | |||
| |||
2006 | 1.97±0.67 | 2.25±0.77 | <0.001¶ |
| |||
2007 | 2.25±0.76 | 2.18±0.72 | |
| |||
2008 | 2.27±0.79 | 2.09±0.73 | |
| |||
2009 | 2.32±0.74 | 2.16±0.74 | |
| |||
2010 | 2.44±0.87 | 2.20±0.76 | |
| |||
2011 | 2.54±0.87 | 2.21±0.77 | |
| |||
2012 | 2.69±1.02 | 2.35±0.91 | |
| |||
2013 | 3.02±1.13 | 2.55±0.96 |
*Data presented as mean±standard deviation. †Mann-Whitney U test for continuous variables. ‡Chi-square test for categorical variables. §MMSE score±12 months of onset of psychosis. ¶Univariate regression analysis. H&Y: Modified Hoehn and Yahr Staging Scale, MMSE: Mini-Mental State Examination