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Effect of MIP-1α gene deletion on eosinophil recruitment into the lungs of mice infected with C. neoformans 52D or 145A (2 weeks postinfection). Leukocytes were isolated from infected lungs of WT and MIP-1α KO mice following enzymatic dispersion of whole lungs. Data (means ± SE) are percentages of eosinophils in cytospun preparations of lung leukocytes (n = 15 to 17 mice per group). Asterisk, P < 0.05, in comparison with 52D-infected group; dagger, P < 0.05, in comparison with WT mice.
