Pao2 and Paco2 before and during apnoea. Figures shown are mean (standard deviation) arterial oxygen and carbon dioxide tensions (kPa). TA, onset of apnoea; TA+x, apnoea duration where x denotes min after TA. Figures before apnoea (at baseline breathing air, and at the end of preoxygenation) include data from all participants in the high flow nasal oxygen (HFNO; where data are available, n=39) and facemask oxygen (FM, n=39) groups. During apnoea, figures include data only from the 60 participants who completed 18 min of apnoea (HFNO, n=36; FM, n=24). Comparisons were made using the independent t-test.