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. 2022 Nov 5;44(3):1079–1093. doi: 10.1002/hbm.26140

FIGURE 1.

FIGURE 1

(a) Topography of behavioral variant frontotemporal dementia (bvFTD) related pattern identified in cohort Slovenia a (bFDRP‐SLOV), (b) bFDRP‐SLOV expression scores of bvFTD patients and normal controls (NC) from the identification cohort Slovenia a and validation cohorts Slovenia B, USA, and Germany, and (c) correlation between bFDRP‐SLOV and mini‐mental state examination (MMSE) scores in bvFTD patients from all three sites. (a) bFDRP was identified using multivariate SSM‐PCA analysis of FDG‐PET images from 20 probable bvFTD patients and 20 age‐matched HC. Relative metabolic decrease is color‐coded blue and relative metabolic increase red. Coordinates in the axial (z), coronal (y), and sagittal (x) planes are in Montreal Neurological Institute (MNI) standard space. (b) Mean values and standard errors are presented. Vertical lines separate cohorts from different centers. One‐way ANOVA among all groups (including other dementia disorders—see text and Figure S3) was performed (F 14,271 = 27.0, p < .0001) and results of post‐hoc Bonferroni's multiple comparison test between identification bvFTD group and other groups are presented (***p < .001, ****p < .0001, ns: p > .05). (c) Linear regression line with 95% confidence interval is presented.