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. 2023 Jan 25;18(1):e0280754. doi: 10.1371/journal.pone.0280754

Table 1. Characteristics of the included studies (N = 8).

Author and year Country Study design Sample size in singleton GDM Sample size in twin GDM Study participants Mean age
Ashwal 2021 Canada Retrospective cohort 1893 180 All women with a singleton or twin pregnancy (with outcome reported separately for GDM patients with singleton or twin pregnancy) who were followed up at a single tertiary referral center (Sunnybrook Health Sciences Center, Toronto, Ontario, Canada) between January 1, 2011, and April 31, 2020 S = 34.6
T = 35.1
Guillén-Sacoto 2017 Spain Retrospective observational 122 62 GDM pregnancies, women were followed throughout their pregnancy, then underwent postpartum examination between January 1991 and December 2015. S = 35.5
T = 35.8
Guillén-Sacoto 2018 Spain Retrospective observational 240 120 Pregnant women with GDM: 120 pregnancies twins and 240 singleton pregnancies as controls S = 35.1
T = 35.3
Hiersch 2019 Canada Retrospective cohort 16731 649 All twin and singleton live births in Ontario, Canada, 2012–2016 with pregnancy outcomes compared between women with vs without gestational diabetes mellitus, analysed separately for twin and singleton births S = 33.1
T = 34
Lai 2015 Canada Retrospective analysis 18137 805 Singleton and twin GDM pregnancies resulting in live/still births in Alberta NR
Sheehan 2019 Australia Retrospective cohort 1370 39 All women who delivered at the Royal Women’s Hospital, Melbourne, between January 2016 and December 2017 with outcome reported separately between GDM singleton and GDM twin pregnancy NR
Weiner 2018 Israel Retrospective analysis 228 114 All deliveries of singleton and twin pregnancies complicated by GDM at a single university-affiliated hospital between 1/2008-10/2016 S = 32.3
T = 31.9
Xue 2019 China Retrospective analysis 572 286 Twin and singleton pregnancies complicated by GDM, which delivered in Peking University First Hospital from January 1st, 2012—December 31st, 2017 S = 32
T = 33

S-Singleton pregnancy; T-Twin pregnancy; NR-Not reported