TABLE 1.
V. cholerae strains used in this study
| Strain | Genotypea | Toxin production
|
Reference | ||
|---|---|---|---|---|---|
| CT | RTX | HAPb | |||
| Classical | |||||
| O395 | Wild type, Stpr | + | − | − | 24 |
| O395N1 | O395 ΔctxA | − | − | − | 25 |
| O395NT | O395 ΔctxAB | − | − | − | 25 |
| KKV62 | O395 ΔtoxR | − | − | − | 29 |
| KKV163 | O395 ΔtoxT | − | − | − | 29 |
| E1 Tor | |||||
| N16961 | Inaba wild type, Stpr | + | + | + | 5 |
| E7946 | Ogawa wild type, Stpr | + | + | + | 24 |
| Bah1 | E7946 Δcore | − | + | + | 32 |
| Bah1P | E7946 Δcore ΔhapA | − | + | − | 6 |
| Bah2P | E7946 ΔattRS ΔhapA | − | − | − | 6 |
| P27459 | Inaba wild type | + | + | + | 24 |
| Bang1P | P27459 Δcore ΔhapA | − | + | − | This study |
| Bang2P | P27459 ΔattRS ΔhapA | − | − | − | This study |
| P4 | P27459 ΔctxAB | − | + | + | 8 |
| KFV82 | P27459 ΔhapA ΔrtxCABD | + | − | − | This study |
| KFV105 | P27459 ΔctxAB ΔhapA ΔrtxCABD | − | − | − | This study |
a
Δcore mutations have deletion of orfU, ace, cep, zot, and ctxAB from the CTXΦ core region (32). ΔattRS refers to deletion of the entire CTXΦ prophage and flanking DNA, including the 3′ end of the rtxA gene (21, 32) ΔrtxCABD is identical to the naturally occurring deletion of classical strain O395 (21).
b
HA/protease.