| Critical commercial assays |
|
| Neurology 4-plex B kit |
Single Molecular Array Technology (SIMOA® SR-XTM Analyzer, Quanterix Corporation, MA) |
Cat# 103345 |
| U-PLEX Biomarker Group 1 (hu) 71-Plex |
Meso Scale Discovery (MSD) |
Cat# K15081K |
| V-PLEX Vascular Injury Panel 2 Human Kit |
Meso Scale Discovery (MSD) |
Cat# K15198D |
| V-PLEX Angiogenesis Panel 1 Human Kit |
Meso Scale Discovery (MSD) |
Cat# K15190D |
|
| Deposited data |
|
| Combined multi-omics dataset |
Human Trisome Project |
Synapse data: https://www.synapse.org/#!Synapse:syn35991637.1/datasets/
|
| Plasma proteomics data |
Human Trisome Project |
Synapse data: https://doi.org/10.7303/syn31488781
|
| Neurodegeneration biomarker data |
Human Trisome Project |
Synapse data: https://doi.org/10.7303/syn35993837
|
| Inflammatory marker data |
Human Trisome Project |
Synapse data: https://doi.org/10.7303/syn31475487
|
|
| Software and algorithms |
|
| R |
R Foundation for Statistical Computing |
v3.6.1 RRID:SCR_001905, https://www.R-project.org/
|
| RStudio |
RStudio, Inc. |
v1.2.5025 RRID:SCR_000432, http://www.rstudio.com/
|
| Bioconductor |
N/A |
v3.11 RRID:SCR_006442, https://bioconductor.org/
|
| limma package for R |
N/A |
v3.44.3 RRID:SCR_010943, https://bioconductor.org/packages/release/bioc/html/limma.html
|
| SomaDataIO R package |
SomaLogic |
v3.1.0 RRID: SCR_022198, https://github.com/SomaLogic/SomaDataIO
|
| ggplot2 package for R |
N/A |
v3.3.1 RRID:SCR_014601, https://ggplot2.tidyverse.org/
|
| fgsea package for R |
N/A |
v 1.14.0 RRID:SCR_020938, https://github.com/ctlab/fgsea
|
|
ConsensusClusterPlus package for R |
Bioconductor |
v1.52.0 RRID:SCR_016954, https://git.bioconductor.org/packages/ConsensusClusterPlus
|
