Clone assignment and CNA inference results from InferCNV, STARCH-nonspatial, and STARCH on spatial transcriptomics data from four layers of a breast cancer biopsy. For each method, CNA inference was performed separately for each of the four layers 1-4 ordered from top to bottom. (a-c) Clone assignment and copy number profiles from InferCNV, STARCH-nonspatial and STARCH. (d-f) Average copy number distance between layers 1 and 2, 2 and 3, and 3 and 4.